2 edition of Post-translational modifications in health and disease found in the catalog.
Post-translational modifications in health and disease
Cecilio J. Vidal
Includes bibliographical references and index.
|Statement||Cecilio J. Vidal, editor|
|LC Classifications||QH623 .P67 2010|
|The Physical Object|
|Pagination||xiii, 486 p. :|
|Number of Pages||486|
|LC Control Number||2010937213|
Molecular mechanisms and physiology of disease: Implications for Epigenetics and Health: Medicine & Health Science Books @ Tzouros' major area of expertise encompasses the quantification of post-translational modifications, such as phosphorylation and ubiquitylation, which can be implicated in disease. This serves to address important questions related to target biology, drug effect, mode of .
Ratnakumar, Kajan ; Kapoor, Avnish ; Bernstein, Emily. / Regulation of chromatin structure and transcription via histone modifications. Post-Translational Modifications in Health and Disease. editor / Cecilio Vidal. pp. (Protein Reviews).Cited by: 1. It also describes how post-translational modifications control Rho activity and how this is exploited by pathogenic bacteria. Part 3 explores several examples of the variety of pathophysiological processes controlled by Rho signaling, and gives a successful example of translational research, from the inhibition of Rho activation to the.
Cancer and Gene Regulation There are many examples of how translational or post-translational modifications of proteins arise in cancer. A variety of modifications can be found in cancer cells that cause effects that range from the increased translation of a protein to changes in protein phosphorylation to alternative splice variants of a Author: Lisa Bartee, Walter Shriner, Catherine Creech. SV BMI Molecular and cellular biology Neuroscience Structural biology Translational research; Laboratories LMNN Research Post-translational Modifications (PTMs): Deciphering the PTM codes of proteins and uncovering their potential as therapeutic targets and molecular switches for regulating protein functions in health and disease.
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Post-Translational Modifications in Health and Disease. Book January (ed.), P ost-T ranslational Modif ications in Health and Disease. Post-translational modifications serve many different purposes in several cellular processes such as gene expression, protein folding and transport to appropriate cell compartment, protein-lipid and protein-protein interactions, enzyme regulation, signal transduction, cell proliferation and differentiation, protein stability, recycling and degradation.
Post-translational Modifications in Health and Disease provides the reader with nineteen reviews that stimulate further investigations in the proteomic field - focusing on functional and pathological aspects of protein prenylation, the incorporation of glycosylphosphatidylinositol (GPI) moieties, oxidation, nitrosylation, glycosylation, and.
Request PDF | Post-Translational Modifications in Health and Disease | Post-translational modifications serve many different purposes in a wide variety of cellular processes,such as protein.
Get this from a library. Post-translational modifications in health and disease. [Cecilio J Vidal;] -- (Publisher-supplied data) Post-translational modifications serve many different purposes in several cellular processes such as gene expression, protein folding and transport to appropriate cell.
Alfredo Ulloa-Aguirre, P. Michael Conn, in Cellular Endocrinology in Health and Disease, Post-Translational Modifications Regulating GPCRs Targeting to the PM. Post-translational modifications are also important for GPCR targeting to the cell surface. Two modifications are particularly important: palmitoylation and N-linked.
The accumulation of abnormal protein aggregates represents a universal hallmark of neurodegenerative diseases (NDDs). Post-translational modifications (PTMs) regulate protein structure and function. Dysregulated PTMs may influence the propensity for protein aggregation in NDD-proteinopathies.
To investigate this, we systematically reviewed the literature to evaluate effects of PTMs on. Post-translational modification (PTM) refers to the covalent and generally enzymatic modification of proteins following protein ns are synthesized by ribosomes translating mRNA into polypeptide chains, which may then undergo PTM to form the mature protein product.
PTMs are important components in cell signaling, as for example when prohormones are converted to hormones. Post-Translational Modifications in Health and Disease. Protein Reviews (Book 13) Thanks for Sharing. You submitted the following rating and review. We'll publish them on our site once we've reviewed : Springer New York.
Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology.
Connexins: Synthesis, Post-Translational Modifications, and Trafficking in Health and Disease by Trond Aasen 1,*, Scott Johnstone 2,3,*, Laia Vidal-Brime 1, K. Sabrina Lynn 4 and Michael Koval 4,5,*Cited by: Read "Post-Translational Modifications in Health and Disease" by available from Rakuten Kobo.
Post-translational modifications serve many different purposes in Brand: Springer New York. Book can to be your best friend when you getting tension or having big problem with your subject. If you can make reading a book Post-Translational Modifications in Health and Disease: 13 (Protein Reviews) being your habit, you can get much more advantages, like add your capable, increase your knowledge about a number of or all subjects.
Posttranslational Modifications In Health And Disease Epub Download FREE READING - Post Translational Modifications Serve Many Different Purposes In A Wide Variety Of Cellular Processessuch As Protein Synthesis Folding Stability.
Keywords:Post-translational modifications, Alzheimer, SUMOylation, Ubiquitinatin, Phosphorylation, Nitrosylation, Acetylation. Abstract:Background: Alzheimer's disease (AD) is a neurodegenerative disorder recognized as the most common cause of chronic dementia among the ageing population.
AD is histopathologically characterized by progressive Cited by: Advanced Review Post-translational modiﬁcation: nature’s escape from genetic imprisonment and the basis for dynamic information encoding Sudhakaran Prabakaran,1 Guy Lippens,2 Hanno Steen3 and Jeremy Gunawardena1∗ We discuss protein post-translational modiﬁcation (PTM) from an information processing Size: KB.
A Comprehensive Guide to Crucial Attributes of Therapeutic Proteins in Biological Pharmaceuticals With this book, Dr. Raju offers a valuable resource for professionals involved in research and development of biopharmaceutical and biosimilar drugs. This is a highly relevant work, as medical practitioners have increasingly turned to biopharmaceutical medicines in their search for safe and.
Taylor D.R., Hooper N.M. () GPI-Anchored Proteins in Health and Disease. In: Vidal C. (eds) Post-Translational Modifications in Health and Disease. Protein Reviews, vol Cited by: 7. Post-translational modification of proteins is important for the regulation of cellular processes, including the cellular localization of protein, the regulation of protein function, and protein complex formation.
Post-translational modification of proteins is part of what makes proteomics so much more challenging than genomics. Not only does the proteomic “alphabet” contain more letters Cited by: From the leading author in the field, known around the world for his work and his authoritative publications, the contents of this book have been selected so as to reflect their relative importance for biopharmaceuticals.
As a result, around half of the book is devoted to protein glycosylation, while the remainder is made up of other modifications, such as carboxylation, Author: Gary Walsh. Post-translational modification regulates the qualitative and quantitative control of a huge number of proteins in eukaryotes.
Multiple sites may be targeted by a wide range of modifications, such as glycosylation, sulphation, methylation, sumoylation, citrullination, farnesylation, biotinylation, ubiquitination and proteolytic cleavage. These complex processes require a multitude of specific Cited by: 4.Consequently, the analysis of proteins and their post-translational modifications is particularly important for the study of heart disease, cancer, neurodegenerative diseases and diabetes.
The characterization of PTMs, although challenging, provides invaluable insight .Shared Interests and Overlaps. Genetics of Health and Disease (GHD) Applications focused on Mendelian gene discovery with complex genetic or genomic methods may reviewed by GHD; genetic and genomic studies of Mendelian disease pathogenesis may be reviewed by TAG.
Gene and Drug Delivery (GDD) Applications focused on developing gene delivery methods may be reviewed by GDD; .